NovaBay Pharmaceuticals Retains The Investor Relations Group of New York

By November 20, 2007

NovaBay Pharmaceuticals, Inc. (Amex & TSX: NBY), a biopharmaceutical company focused on developing innovative product candidates targeting the treatment or prevention of a wide range of infections in hospital and non-hospital environments, has retained the New York City-based The Investor Relations Group, Inc. (IRG), to serve as its investor relations and corporate communications firm.

“Having recently completed our initial public offering, we remain focused on moving forward with our clinical development of non-antibiotic anti-infective products targeting the treatment or prevention of a wide range of infections in hospital and community environments,” said Ron Najafi, Ph.D., Chairman and Chief Executive Officer of NovaBay. “With leading pharmaceutical partners and several product candidates in the pipeline, we believe The Investor Relations Group will play an integral role in communicating NovaBay’s message to the investment community and the general media.”

About The Investor Relations Group, Inc.

The Investor Relations Group, Inc. (IRG) offers a full-service corporate communications program designed to suit the many unique needs of small-cap companies. The program utilizes a proprietary, targeted approach to reach institutional investors, analysts, and the media-at-large. For further information, please visit the company’s website at www.investorrelationsgroup.com.

About NovaBay

NovaBay Pharmaceuticals, Inc. is a biopharmaceutical company focused on developing innovative product candidates targeting the treatment or prevention of a wide range of infections in hospital and non-hospital environments. NovaBay has discovered and is developing a class of antimicrobial compounds, which it has named Aganocide® compounds, which are based upon small molecules that are generated by white blood cells that defend the body against invading pathogens. NovaBay believes that Aganocide® compounds could form a platform on which to create a variety of products to address differing needs in the treatment and prevention of bacterial and viral infections, including Methicillin-Resistant Staphylococcus aureus (MRSA). NovaBay has entered into a licensing and research collaboration agreement with an affiliate of Alcon, Inc. for use of the Aganocide® compounds in the eye, ear and sinus and in contact lens solutions and a license agreement with an affiliate of Kinetic Concepts, Inc. for the use of NovaBay’s NeutroPhase product in woundcare applications.

NovaBay(TM), Aganocide® and NeutroPhase(TM) are trademarks of NovaBay Pharmaceuticals, Inc. All other trademarks and trade names are the property of their respective owners.

For more information visit the Company’s website at www.novabaypharma.com

Forward Looking Statement

This release contains forward-looking statements, which are based upon management’s current expectations, assumptions, estimates, projections and beliefs. These statements include, but are not limited to, statements regarding the role of IRG and the development and potential benefits of, and the market opportunities for, NovaBay’s product candidates. Forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause actual results or achievements to be materially different and adverse from those expressed in or implied by the forward-looking statements. Factors that might cause or contribute to such differences include, but are not limited to, risks and uncertainties relating to difficulties or delays in discovery, development, testing, regulatory approval, production and marketing of the company’s product candidates, unexpected adverse side effects or inadequate therapeutic efficacy of the product candidates, the uncertainty of patent protection for the company’s intellectual property or trade secrets, the company’s ability to obtain additional financing as necessary and unanticipated research and development and other costs. The forward-looking statements in this release speak only as of this date, and NovaBay disclaims any intent or obligation to revise or update publicly any forward-looking statement except as required by law.

Contact

Investor Relations:
The Investor Relations Group
Adam Holdsworth / Rachel Colgate / Erica Ruderman
212-825-3210

Or

Media Relations:
Janet Vasquez / Susan Morgenbesser
212-825-3210

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